CHO-K1-NK3-Stable Cell Line

Introduction

Recombinant CHO-K1 cells have been created to stably overexpress the human tachykinin receptor 3 (NK3) on their surface, and they contain high levels of the G protein Gαq, which is involved in coupling with the receptor to facilitate downstream signaling pathways.

Application

Drug screening and biological assays

Background

Neurokinin 3 receptor (NK3R), also known as tachykinin receptor 3 (TACR3), is a G protein-coupled receptor that binds neurokinin B, a neuropeptide involved in various physiological processes including reproduction, stress response, and neuroendocrine regulation.

Product Information