CHO-K1-OPRM1/Gα15-Stable Cell Line
| Catalog Number |
CBCL-0140 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
Recombinant CHO-K1 cells have been engineered to stably overexpress human opioid receptor mu 1 (OPRM1) on their surface. These cells contain high levels of both G protein Gαi and Gαq, which are crucial for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
OPRM1 encodes the mu-opioid receptor, a key receptor in the endogenous opioid system. It is involved in pain perception, analgesia, and addiction, and is the principal target of endogenous opioid peptides and opioid analgesic agents.
Product Information
| Category |
GPCR Cell Lines |
| Cell Line Name |
CHO-K1-OPRM1/Gα15-Stable Cell Line |
| Protein Family |
Opioid & opioid-like receptor |
| Gene |
OPRM1 |
| NCBI Gene ID |
4988 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B |
| Freeze Medium |
45% culture medium + 45% FBS + 10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
