CHO-K1-PAR4-Stable Cell Line
| Catalog Number |
CBCL-0161 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-PAR4-Stable Cell Line is designed to stably express the PAR4 (protease-activated receptor 4).
Application
Drug screening and biological assays
Background
PAR4, or proteinase-activated receptor 4, is another member of the proteinase-activated receptor family. It is activated by proteolytic cleavage by thrombin and other proteases. Activation of PAR4 leads to platelet activation, aggregation, and the release of inflammatory mediators. It is involved in the pathogenesis of thrombosis and cardiovascular diseases. PAR4 antagonists are being investigated as potential antithrombotic agents.
Product Information
| Category |
GPCR Cell Lines |
| Cell Line Name |
CHO-K1-PAR4-Stable Cell Line |
| Protein Family |
Protease-activated receptor |
| Gene |
PAR4/F2RL3 |
| NCBI Gene ID |
9002 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12 K (Kaighn’s), 10% FBS, 400 μg/ml G418 |
| Freeze Medium |
45% culture medium + 45% FBS + 10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
