CHO-K1-PD-1-Stable Cell Line
| Catalog Number | CBCL-0519 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-PD-1-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human programmed cell death 1 (PD-1) on their surface. The surface expression of PD-1 is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
PD-1 (Programmed Death-1) is an immune checkpoint receptor expressed on activated T-cells. It binds to its ligands PD-L1 and PD-L2, inhibiting T-cell activation and promoting immune tolerance, which is exploited by tumors to evade immune surveillance.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-PD-1-Stable Cell Line |
| Protein Family | Programmed cell death protein 1 family |
| Gene | PD-1 |
| NCBI Gene ID | 5133 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.