CHO-K1-SST1/Gqi5-Stable Cell Line

Catalog Number	CBCL-0162
Price	Online Inquiry
Unit Quantity	1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-SST1/Gqi5-Stable Cell Line is engineered to stably express the SST1 (somatostatin receptor 1) and the Gqi5 protein.

Application

Drug screening and biological assays

Background

SSTR1, or the somatostatin receptor 1, is a G-protein coupled receptor that binds somatostatin, a peptide hormone with inhibitory effects on growth hormone, insulin, and glucagon secretion. SSTR1 activation leads to decreased intracellular cAMP levels and inhibition of cell proliferation. It is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract, and is involved in regulating hormone secretion, neurotransmission, and cell growth.

Product Information

Category	GPCR Cell Lines
Cell Line Name	CHO-K1-SST1/Gqi5-Stable Cell Line
Protein Family	Somatostatin receptor
Gene	SST1/SSTR1
NCBI Gene ID	6751
Species	Hamster
Host Cell Line	CHOK1
Cell Type	Chinese hamster ovary cell line
Morphology	Epithelial
Growth Properties	Adherent
Recommended Medium	Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B
Freeze Medium	45% culture medium + 45% FBS + 10% DMSO
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.