CHO-K1-Tim3-Stable Cell Line
| Catalog Number | CBCL-0535 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-Tim3-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human hepatitis A virus cellular receptor 2 (TIM3) on their surface. The surface expression of TIM3 is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
TIM-3 (T cell immunoglobulin and mucin domain-3) is an immune checkpoint receptor expressed on exhausted T cells, NK cells, and macrophages. It binds to galectin-9, HMGB1, or CEACAM-1, delivering inhibitory signals that promote T cell apoptosis and immune suppression. TIM-3 is a potential target for reversing T cell exhaustion in cancer and chronic infections.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-Tim3-Stable Cell Line |
| Protein Family | T cell immunoglobulin and mucin domain-3 family |
| Gene | Tim3 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.