CHO-K1-VISTA-Stable Cell Line
| Catalog Number | CBCL-0536 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-VISTA-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human V-set immunoregulatory receptor (VISTA) on their surface. The surface expression of VISTA is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
VISTA (V-domain Ig suppressor of T cell activation) is an immune checkpoint protein expressed on hematopoietic cells and tumor cells. It functions as a ligand for multiple receptors (e.g., PSGL-1) and suppresses T cell activation by inhibiting TCR signaling. VISTA is overexpressed in various cancers and correlates with poor prognosis.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-VISTA-Stable Cell Line |
| Protein Family | V-domain Ig suppressor of T cell activation family |
| Gene | VISTA |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.