Catalog Number | CBCL-0177 |
Price | Online Inquiry |
Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Recombinant CHO-K1 cells have been engineered to stably overexpress the human vasoactive intestinal peptide receptor 2 (VPAC2) on their surface, and they contain high levels of the G protein Gαs, which is involved in coupling with the receptor to facilitate downstream signaling pathways.
Drug screening and biological assays
Vasoactive intestinal peptide receptor 2 (VPAC2 or VIPR2) is another G protein-coupled receptor for VIP and PACAP, with similar functions to VPAC1 but with different tissue distribution and regulatory mechanisms.
Category | GPCR Cell Lines |
Cell Line Name | CHO-K1-VPAC2/Gα15-Stable Cell Line |
Protein Family | VIP and PACAP receptor |
Gene | VPAC2/VIPR2 |
NCBI Gene ID | 7434 |
Species | Hamster |
Host Cell Line | CHOK1 |
Cell Type | Chinese hamster ovary cell line |
Morphology | Epithelial |
Growth Properties | Adherent |
Recommended Medium | Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B |
Freeze Medium | 45% culture medium + 45% FBS + 10% DMSO |
Storage Method | Frozen in liquid nitrogen. |
Stability | Validated for at least 10 passages |
Mycoplasma | Negative |
Sterility Testing | Negative |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |