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CHOK1-CRE-Luc2-PTH1R-high expression-Stable Cell Line

Catalog Number CBCL-0310
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

This stable CHO-K1 cell line expresses exogenous luciferase under the control of the cAMP response element (CRE) and also expresses the human PTH1R gene at high levels, facilitating studies of CRE-dependent gene expression and PTH1R signaling.

Application

Drug screening and biological assays

Background

PTH1R is a G protein-coupled receptor for parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP). It regulates calcium and phosphate homeostasis, bone remodeling, and other physiological processes.

Product Information

Category Luciferase Reporter Cell Lines
Cell Line Name CHOK1-CRE-Luc2-PTH1R-high expression-Stable Cell Line
Protein Family Parathyroid hormone receptor family
Gene PTH1R
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin, HygromycinB
Recommended Medium RPMI1640+10%FBS+10µg/mL Puromycin+750µg/mL Hygromycin B
Freeze Medium 70% RPMI1640+20% FBS+10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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