| Catalog Number | CBCL-0310 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
This stable CHO-K1 cell line expresses exogenous luciferase under the control of the cAMP response element (CRE) and also expresses the human PTH1R gene at high levels, facilitating studies of CRE-dependent gene expression and PTH1R signaling.
Drug screening and biological assays
PTH1R is a G protein-coupled receptor for parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP). It regulates calcium and phosphate homeostasis, bone remodeling, and other physiological processes.
| Category | Luciferase Reporter Cell Lines |
| Cell Line Name | CHOK1-CRE-Luc2-PTH1R-high expression-Stable Cell Line |
| Protein Family | Parathyroid hormone receptor family |
| Gene | PTH1R |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin, HygromycinB |
| Recommended Medium | RPMI1640+10%FBS+10µg/mL Puromycin+750µg/mL Hygromycin B |
| Freeze Medium | 70% RPMI1640+20% FBS+10% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |