Catalog Number | CBCL-561 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
BxPC-3 cell line stable expressing exogenous human CLDN18 gene isoform 2
Drug screening and biological assays
CLDN18.2 is the isoform 2 of the claudin 18 gene, which belong to the lager claudin family and play the important role in cell tight junction in epithelial cells. The identification as a tumor target of CLDN18.2 has led to the repaid progress of antibody treatment of gastrointestinal adenocarcinoma and pancreatic tumors.
Species | Human |
Host Cell Line | BxPC-3 |
Cell Type | Pancreatic adenocarcinoma cell line |
Stability | Stable in culture over 10 passages |
Growth Properties | Adherent |
Pharmaceutical Target | Immune Molecules |
Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
Selection Marker | Puromycin |
Morphology | Epithelial |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Doubling Time | Approximately 30 hours |
QC | WB |
Biosafety Level | BSL-1 |
Shipping | Shipping in dry ice |
Caution | For Research Use Only |