| Catalog Number | CBCL-333 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Stable HEK293T cell line expressing exogenous cyno GUCY2C gene
Drug screening and biological assays
Guanylyl cyclase C (GUCY2C) is a particulate guanylyl cyclase receptor, GUCY2C belongs to a family of mucosal cyclase receptors. It is a transmembrane receptor for the endogenous hormonal ligands: guanylin and uroguanylin. GUCY2C is expressed only in intestinal epithelial cells and by nearly 100% of colorectal cancers. They play an important role in preventing colorectal cancer.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Cyno GUCY2C Stable 293T Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Human |
| Host Cell Line | 293T |
| Cell Type | Human embryonic kidney cells |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:5. |
| Doubling Time | Approximately 30 hours |
| Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |