Cyno TREM2-DAP12 Stable 293T Cell Line

Catalog Number	CBCL-390
Price	Online Inquiry
Unit Quantity	1x10⁶ cells / 1.0 ml

Introduction

Stable 293T cell line expressing exogenous cyno TREM2-DAP12 gene

Application

Drug screening and biological assays

Background

TERM2 is a membrane protein which expressed primarily in immune cells across many different tissues, and form a receptor signaling complex with TYROBP, also named as DAP12, then mediates signaling and cell activation after binding serval ligands, it plays an important role in different inflammatory diseases, especially Alzheimer's disease, and is also believed as a promising target for cancer therapy.

Product Information

Category	Immune Molecules Cell Lines
Cell Line Name	Cyno TREM2-DAP12 Stable 293T Cell Line
Pharmaceutical Target	Immune Molecules
Species	Human
Host Cell Line	293T
Cell Type	Human embryonic kidney cells
Morphology	Monolayer
Growth Properties	Adherent
Selection Marker	Puromycin and hygromycin B
Seeding Density	Thaw entire contents into an appropriate T25 flask.
Subculture Ratio	Recommended a ratio of 1:4-1:8.
Doubling Time	Approximately 24 hours
Recommended Medium	DMEM + 10% FBS + 1 μg/ml Puromycin
Storage Method	Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability	Stable in culture over 10 passages
QC	WB
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.