Online Inquiry

Daudi-PD-1-Stable Cell Line

Catalog Number CBCL-0522
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The Daudi-PD-1-Stable Cell Line consists of recombinant Daudi cells that stably overexpress human programmed cell death protein 1 (PD-1) on their surface. The surface expression of PD-1 is confirmed by FACS analysis.

Application

Drug screening and biological assays

Background

PD-1 (Programmed Death-1) is an immune checkpoint receptor expressed on activated T-cells. It binds to its ligands PD-L1 and PD-L2, inhibiting T-cell activation and promoting immune tolerance, which is exploited by tumors to evade immune surveillance.

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name Daudi-PD-1-Stable Cell Line
Protein Family Programmed cell death protein 1 family
Gene PD-1
NCBI Gene ID 5133
Species Human
Host Cell Line Daudi
Cell Type Human Burkitt's lymphoma cells
Morphology Lymphoblastoid
Growth Properties Suspension
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.