Catalog Number | CBCL-295 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
Stable HEK293T cell line expressing exogenous Dog CCR8 gene
Drug screening and biological assays
CCR8, also known as CD198, is a member of the chemokine receptor subfamily and belongs to the G-protein coupled receptor, which is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.
Category | Immune Molecules Cell Lines |
Cell Line Name | Dog CCR8 HA Stable 293T Cell Line |
Pharmaceutical Target | Immune Molecules |
Species | Human |
Host Cell Line | 293T |
Cell Type | Human embryonic kidney cells |
Morphology | Monolayer |
Growth Properties | Adherent |
Selection Marker | Puromycin |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Doubling Time | Approximately 30 hours |
Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Stability | Stable in culture over 10 passages |
QC | WB |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |