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EGFR T790M/C797S/ L858R Stable NCI-H1975 Cell Line

Catalog Number CBCL-431
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable NCI-H1975 cell clone bearing endogenous EGFR C797S mutations

Application

Drug screening and biological assays

Background

EGFR, the epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase, and activated by binding of its specific ligand, such as epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The overexpression or overactivity of EGFR has associated with a number of cancers, including the lung cancer and colon cancer.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name EGFR T790M/C797S/ L858R Stable NCI-H1975 Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line NCI-H1975
Cell Type Human non-small cell lung cancer cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Hygromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:3-1:6.
Recommended Medium RPMI 1640 + 10% FBS + 100 μg/ml Hygromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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