| Catalog Number | CBCL-0315 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
This stable HCC1954 cell line expresses exogenous luciferase under the control of the STAT3 signaling pathway, enabling studies of STAT3-dependent gene expression and signaling events.
Drug screening and biological assays
STAT3 (Signal Transducer and Activator of Transcription 3) is a transcription factor that plays a key role in cell growth, survival, and differentiation. It is activated by various cytokines and growth factors.
| Category | Luciferase Reporter Cell Lines |
| Cell Line Name | HCC1954-STAT3-Luc2-Reporter Cell Line |
| Protein Family | Signal transducer and activator of transcription family |
| Gene | STAT3 |
| NCBI Gene ID | 6774 |
| Species | Human |
| Host Cell Line | HCC1954 |
| Cell Type | Human breast cancer |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Hygromycin B |
| Recommended Medium | RPMI1640+10%FBS+150µg/mL Hygromycin B |
| Freeze Medium | 70% RPMI1640+20% FBS+10% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |