HEK293-5-HT2C-Stable Cell Line
| Catalog Number | CBCL-0052 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
Recombinant HEK293 cells have been developed to stably overexpress human 5-hydroxytryptamine receptor 2C (5-HT2C) on their surface. These cells contain high levels of the G protein Gαq, which is crucial for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
This gene encodes a receptor for serotonin, a neurotransmitter that plays a key role in regulating mood, appetite, and sleep. The receptor is a target for various drugs used to treat psychiatric disorders, including antidepressants and antipsychotics.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | HEK293-5-HT2C-Stable Cell Line |
| Protein Family | 5-Hydroxytryptamine receptor |
| Gene | 5-HT2C/HTR2C |
| NCBI Gene ID | 3358 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.