HEK293-FP/Gα15-Stable Cell Line

Catalog Number	CBCL-0155
Price	Online Inquiry
Unit Quantity	1 x 10^6 cells / 1.0 ml

Introduction

The HEK293-FP/Gα15-Stable Cell Line is designed to stably express the FP (prostaglandin F receptor) and the Gα15 protein.

Application

Drug screening and biological assays

Background

PTGFR, or the prostaglandin F receptor, is a G-protein coupled receptor that binds prostaglandin F2α (PGF2α). PGF2α is involved in various physiological processes, including smooth muscle contraction, uterine contraction during labor, and the regulation of ocular pressure. PTGFR activation leads to increased intracellular calcium levels and smooth muscle contraction, making it a target for drugs used to treat conditions such as glaucoma and premature labor.

Product Information

Category	GPCR Cell Lines
Cell Line Name	HEK293-FP/Gα15-Stable Cell Line
Protein Family	Prostanoid receptor
Gene	FP/PTGFR
NCBI Gene ID	5737
Species	Human
Host Cell Line	HEK293
Cell Type	Human embryonic kidney cells
Morphology	Epithelial
Growth Properties	Adherent
Recommended Medium	DMEM, 10% FBS, 200 μg/ml Zeocin, 250 μg/ml G418, 100 μg/ml Hygromycin B
Freeze Medium	45% culture medium + 45% FBS + 10% DMSO
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.