HEK293-FP/Gα15-Stable Cell Line
| Catalog Number | CBCL-0155 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-FP/Gα15-Stable Cell Line is designed to stably express the FP (prostaglandin F receptor) and the Gα15 protein.
Application
Drug screening and biological assays
Background
PTGFR, or the prostaglandin F receptor, is a G-protein coupled receptor that binds prostaglandin F2α (PGF2α). PGF2α is involved in various physiological processes, including smooth muscle contraction, uterine contraction during labor, and the regulation of ocular pressure. PTGFR activation leads to increased intracellular calcium levels and smooth muscle contraction, making it a target for drugs used to treat conditions such as glaucoma and premature labor.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | HEK293-FP/Gα15-Stable Cell Line |
| Protein Family | Prostanoid receptor |
| Gene | FP/PTGFR |
| NCBI Gene ID | 5737 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.