HEK293-GCGR/Gα15-Stable Cell Line
| Catalog Number |
CBCL-0108 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
Recombinant HEK293 cells have been engineered to stably overexpress the human glucagon receptor (GCGR) on their surface, and they contain high levels of the G protein Gαs, which is involved in coupling with the receptor to facilitate downstream signaling pathways.
Application
Drug screening and biological assays
Background
As above, Glucagon receptor (GCGR) is crucial for maintaining glucose homeostasis by responding to glucagon signals.
Product Information
| Category |
GPCR Cell Lines |
| Cell Line Name |
HEK293-GCGR/Gα15-Stable Cell Line |
| Protein Family |
Glucagon receptor |
| Gene |
GCGR |
| NCBI Gene ID |
2641 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
DMEM, 10% FBS, 300 μg/ml geneticin, 50 μg/ml Hygromycin B |
| Freeze Medium |
50% DMEM + 45% FBS + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
