Catalog Number | CBCL-0218 |
Price | Online Inquiry |
Unit Quantity | 2 x 10^6 cells / 1.0 ml |
Recombinant HEK293 cells expressing the firefly luciferase gene under the control of the cAMP response element (CRE), with forced expression of human GIPR (Gastric Inhibitory Polypeptide receptor, NM_000164.4). Activation of GIPR in these cells can be monitored by measuring luciferase activity. The functionality of the GIPR/CRE Luciferase Reporter HEK293 Cell Line was validated using agonists gastric inhibitory peptide (GIP) and tirzepatide hydrochloride, which induce luciferase activity in a dose-dependent manner.
Screen and characterize agonists of human GIPR in a cellular context
GIPR (Gastric Inhibitory Polypeptide Receptor) is a G protein-coupled receptor that binds GIP and regulates insulin secretion and glucose homeostasis.
Category | CRE Reporter Cell Lines |
Cell Line Name | HEK293-GIPR/CRE-Luciferase-Reporter Cell Line |
Protein Family | G protein-coupled receptor family |
Gene | GIPR |
Species | Human |
Host Cell Line | HEK293 |
Cell Type | Human embryonic kidney cells |
Morphology | Epithelial |
Growth Properties | Adherent |
Recommended Medium | DMEM + 10% FBS |
Freeze Medium | 90% complete medium + 10% DMSO |
Storage Method | Frozen in liquid nitrogen. |
Stability | Validated for at least 10 passages |
Mycoplasma | Negative |
Sterility Testing | Negative |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |