Contact Us

USA

Tel:
Fax:
Email:
Europe
Tel:
Email:

HEK293-GIPR/CRE-Luciferase-Reporter Cell Line

Catalog Number CBCL-0218
Price Online Inquiry
Unit Quantity 2 x 10^6 cells / 1.0 ml

Introduction

Recombinant HEK293 cells expressing the firefly luciferase gene under the control of the cAMP response element (CRE), with forced expression of human GIPR (Gastric Inhibitory Polypeptide receptor, NM_000164.4). Activation of GIPR in these cells can be monitored by measuring luciferase activity. The functionality of the GIPR/CRE Luciferase Reporter HEK293 Cell Line was validated using agonists gastric inhibitory peptide (GIP) and tirzepatide hydrochloride, which induce luciferase activity in a dose-dependent manner.

Application

Screen and characterize agonists of human GIPR in a cellular context

Background

GIPR (Gastric Inhibitory Polypeptide Receptor) is a G protein-coupled receptor that binds GIP and regulates insulin secretion and glucose homeostasis.

Product Information

Category CRE Reporter Cell Lines
Cell Line Name HEK293-GIPR/CRE-Luciferase-Reporter Cell Line
Protein Family G protein-coupled receptor family
Gene GIPR
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Recommended Medium DMEM + 10% FBS
Freeze Medium 90% complete medium + 10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
Copyright © 2025 Creative Bioarray. All rights reserved.