| Catalog Number | CBCL-0653 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
A HEK293 cell line that expresses firefly luciferase under the control of the cAMP response element (CRE) and stably expresses human GCGR (Glucagon receptor; NM_000160.5). Activation of GCGR in these cells can be monitored by measuring luciferase activity.
Drug screening and biological assays
GCGR (Glucagon Receptor) is a G protein-coupled receptor that binds to glucagon and mediates its effects on glucose production and release from the liver, playing a role in blood glucose regulation.
| Category | Metabolic Enzymes Cell Lines |
| Cell Line Name | HEK293-Glucagon Receptor (GCGR)/CRE-Luciferase-Reporter Cell Line |
| Protein Family | Glucagon receptor family |
| Gene | GCGR |
| NCBI Gene ID | 2642 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | DMEM medium + 10% FBS |
| Freeze Medium | Cell Freezing Medium |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |