HEK293-H1-Stable Cell Line

Introduction

Recombinant HEK293 cells have been created to stably overexpress the human histamine receptor 1 (H1) on their surface, and they contain high levels of the G protein Gαq, which is involved in coupling with the receptor to facilitate downstream signaling pathways.

Application

Drug screening and biological assays

Background

Histamine H1 receptor (HRH1) is a G protein-coupled receptor that binds histamine, a mediator of allergic and inflammatory responses, as well as a neurotransmitter in the central nervous system.

Product Information