HEK293-Human 4-1BB / TNFRSF9-Stable Cell Line

Catalog Number	CBCL-0570
Price	Online Inquiry
Unit Quantity	5 x 10^6 cells / 1.0 ml

Introduction

The HEK293-Human 4-1BB / TNFRSF9-Stable Cell Line is a stable cell line expressing human 4-1BB / TNFRSF9.

Application

Binding assay by FACS and cell based ELISA

Background

4-1BB (TNFRSF9, CD137) is a co-stimulatory receptor expressed on activated T cells, NK cells, and dendritic cells. It binds to 4-1BB Ligand (TNFSF9) on APCs, promoting T cell proliferation, survival, and cytokine production. 4-1BB agonists are being tested in cancer immunotherapy.

Product Information

Category	Immune Checkpoint Cell Lines
Cell Line Name	HEK293-Human 4-1BB / TNFRSF9-Stable Cell Line
Protein Family	TNF receptor superfamily
Gene	4-1BB (TNFRSF9)
NCBI Gene ID	3604
Species	Human
Host Cell Line	HEK293
Cell Type	Human embryonic kidney cells
Morphology	Epithelial
Growth Properties	Adherent
Selection Marker	Hygromycin B（300 μg/mL)
Recommended Medium	DMEM medium + 10% FBS
Freeze Medium	10% DMSO + 90% FBS
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.