HEK293-Human B7-H4-Stable Cell Line
| Catalog Number | CBCL-0599 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-Human B7-H4-Stable Cell Line is engineered to express full-length human B7-H4 (Uniprot: Q7Z7D3-1), used to mimic cancer target cells.
Application
Useful for cell-based B7-H4 binding assay
Background
B7-H4 (VTCN1) is an inhibitory immune checkpoint molecule expressed on tumor cells and macrophages. It suppresses T cell proliferation and cytokine production by inhibiting TCR signaling. B7-H4 overexpression correlates with poor cancer prognosis and immune suppression.
Product Information
| Category | CAR-T Therapy Cell Lines |
| Cell Line Name | HEK293-Human B7-H4-Stable Cell Line |
| Protein Family | B7 family |
| Gene | B7-H4 |
| NCBI Gene ID | 608 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.