HEK293-Human B7-H4-Stable Cell Line
| Catalog Number |
CBCL-0599 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-Human B7-H4-Stable Cell Line is engineered to express full-length human B7-H4 (Uniprot: Q7Z7D3-1), used to mimic cancer target cells.
Application
Useful for cell-based B7-H4 binding assay
Background
B7-H4 (VTCN1) is an inhibitory immune checkpoint molecule expressed on tumor cells and macrophages. It suppresses T cell proliferation and cytokine production by inhibiting TCR signaling. B7-H4 overexpression correlates with poor cancer prognosis and immune suppression.
Product Information
| Category |
CAR-T Therapy Cell Lines |
| Cell Line Name |
HEK293-Human B7-H4-Stable Cell Line |
| Protein Family |
B7 family |
| Gene |
B7-H4 |
| NCBI Gene ID |
608 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin (2 μg/mL) |
| Recommended Medium |
DMEM + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
