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HEK293-Human BCMA-Stable Cell Line

Catalog Number CBCL-0600
Price Online Inquiry
Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

The HEK293-Human BCMA-Stable Cell Line is engineered to express the receptor full-length human BCMA (Uniprot: Q02223-1). Surface expression of human BCMA is confirmed by flow cytometry.

Application

Useful for cell-based BCMA binding assay.

Background

BCMA (B Cell Maturation Antigen, TNFRSF17) is a receptor expressed on mature B cells and plasma cells. It binds to BAFF and APRIL, promoting B cell survival, proliferation, and antibody production. BCMA is a therapeutic target for multiple myeloma (e.g., CAR-T cells and bispecific antibodies).

Product Information

Category CAR-T Therapy Cell Lines
Cell Line Name HEK293-Human BCMA-Stable Cell Line
Protein Family B-cell maturation antigen family
Gene BCMA
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Selection Marker G418 (200 μg/mL)
Recommended Medium DMEM + 10% FBS
Freeze Medium Serum-free cell cryopreservation medium
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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