HEK293-Human CD40 Ligand / TNFSF5-Stable Cell Line
| Catalog Number |
CBCL-0577 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-Human CD40 Ligand / TNFSF5-Stable Cell Line is a stable cell line expressing human CD40 Ligand / TNFSF5.
Application
Binding assay by FACS and cell based ELISA.
Background
CD40 Ligand (CD40L, TNFSF5) is a co-stimulatory molecule expressed on activated T cells. It binds to CD40 on APCs and B cells, triggering signaling pathways that enhance immune responses, including cytokine production and antibody maturation. CD40L deficiency causes hyper-IgM syndrome.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
HEK293-Human CD40 Ligand / TNFSF5-Stable Cell Line |
| Protein Family |
TNF superfamily |
| Gene |
CD40 Ligand (TNFSF5) |
| NCBI Gene ID |
959 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin (5 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
10% DMSO + 90% FBS |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
