HEK293-Human EGF R (Luc)-Reporter Cell
| Catalog Number |
CBCL-0179 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
The Human EGF R (Luc) HEK293 Reporter Cell has been engineered to express the STAT3 signaling response element and the full-length human EGF R (Uniprot: P00533-1). When stimulated with human EGF protein, the EGF/EGF R interaction drives STAT3-mediated luminescence. Inhibition of EGF binding to EGF R by either anti-EGF or anti-EGF R antibodies results in a decrease in luminescence.
Application
Screen for anti-human EGF R or anti-human EGF neutralizing antibody.
Product Information
| Category |
Receptor Tyrosine Kinase Cell Lines |
| Cell Line Name |
HEK293-Human EGF R (Luc)-Reporter Cell |
| Protein Family |
Epidermal growth factor receptor family |
| Gene |
EGFR |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (40 μg/mL) + Puromycin (2 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
