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HEK293-Human FGF-21 (Luc)-Reporter Cell

Catalog Number CBCL-0197
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Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

The Human FGF-21 (Luc) HEK293 Reporter Cell has been developed to express the SRE signaling response element and the human Klotho beta receptor (Uniprot: Q86Z14). When stimulated with human FGF-21 protein, receptor-mediated signaling activates SRE-mediated luminescence.

Application

Bioactivity detection of human FGF-21 fusion protein.

Background

Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family that acts as a hormone, regulating glucose and lipid metabolism, and has potential therapeutic applications in metabolic disorders.

Product Information

Category Cytokine Receptor Cell Lines
Cell Line Name HEK293-Human FGF-21 (Luc)-Reporter Cell
Protein Family Fibroblast growth factor receptor family
Gene FGF-21
NCBI Gene ID 26291
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.