| Catalog Number | CBCL-0197 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
The Human FGF-21 (Luc) HEK293 Reporter Cell has been developed to express the SRE signaling response element and the human Klotho beta receptor (Uniprot: Q86Z14). When stimulated with human FGF-21 protein, receptor-mediated signaling activates SRE-mediated luminescence.
Bioactivity detection of human FGF-21 fusion protein.
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family that acts as a hormone, regulating glucose and lipid metabolism, and has potential therapeutic applications in metabolic disorders.
| Category | Cytokine Receptor Cell Lines |
| Cell Line Name | HEK293-Human FGF-21 (Luc)-Reporter Cell |
| Protein Family | Fibroblast growth factor receptor family |
| Gene | FGF-21 |
| NCBI Gene ID | 26291 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin (2 μg/mL) + Hygromycin B (20 μg/mL) |
| Recommended Medium | DMEM + 10% FBS |
| Freeze Medium | Serum-free cell cryopreservation medium |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |