HEK293-Human FGF-21 (Luc)-Reporter Cell
| Catalog Number |
CBCL-0243 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
This cell line is a HEK293-based reporter cell line engineered to express the SRE signaling response element and the receptor human Klotho beta (Uniprot: Q86Z14). When stimulated with human FGF-21 protein, receptor-mediated signaling can drive SRE-mediated luminescence.
Application
Bioactivity detection of human FGF-21 fusion protein.
Background
FGF-21 is a member of the fibroblast growth factor family that regulates glucose and lipid metabolism, and has potential therapeutic applications in metabolic disorders.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
HEK293-Human FGF-21 (Luc)-Reporter Cell |
| Protein Family |
Fibroblast growth factor receptor family |
| Gene |
FGF-21 |
| NCBI Gene ID |
26291 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin (2 μg/mL) + Hygromycin B (20 μg/mL) |
| Recommended Medium |
DMEM + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
