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HEK293-Human GUCY2C-Stable Cell Line

Catalog Number CBCL-0623
Price Online Inquiry
Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

The HEK293-Human GUCY2C-Stable Cell Line is engineered to express the receptor full-length human GUCY2C (Uniprot: P25092), used to mimic cancer target cells. Surface expression of human GUCY2C is confirmed by flow cytometry.

Application

Useful for cell-based GUCY2C binding assay.

Background

GUCY2C is a guanylate cyclase receptor that is expressed in intestinal epithelial cells. It is involved in the regulation of intestinal fluid and electrolyte secretion and is a potential biomarker for colorectal cancer.

Product Information

Category CAR-T Therapy Cell Lines
Cell Line Name HEK293-Human GUCY2C-Stable Cell Line
Protein Family Guanylate cyclase family
Gene GUCY2C
NCBI Gene ID 2984
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin (2 μg/mL)
Recommended Medium DMEM + 10% FBS
Freeze Medium Serum-free cell cryopreservation medium
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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