HEK293-Human IL-11 R alpha (Luc)-Reporter Cell
| Catalog Number |
CBCL-0200 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
The Human IL-11 R alpha (Luc) HEK293 Reporter Cell has been created to express the STAT3 signaling response element. Stimulation with human IL-11 protein activates the IL-11/IL-11 R alpha interaction, driving STAT3-mediated luminescence. Inhibition of IL-11 binding to IL-11 R alpha with either anti-IL-11 or anti-IL-11 R alpha antibodies results in a decrease in luminescence.
Application
Screen for anti-human IL-11 or anti-human IL-11 R alpha neutralizing antibody.
Background
IL - 11 R alpha (Interleukin 11 Receptor Alpha) is a cell - surface receptor that binds interleukin - 11 (IL - 11). It plays roles in hematopoiesis, bone metabolism, and tissue repair by mediating the biological effects of IL - 11, such as stimulating cell proliferation and differentiation in various cell types.
Product Information
| Category |
Cytokine Receptor Cell Lines |
| Cell Line Name |
HEK293-Human IL-11 R alpha (Luc)-Reporter Cell |
| Protein Family |
Interleukin receptor family |
| Gene |
IL-11 R alpha |
| NCBI Gene ID |
IL - 10 R alpha: 3587 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (40 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
