HEK293-Human IL-11 R alpha (Luc)-Reporter Cell
| Catalog Number | CBCL-0200 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The Human IL-11 R alpha (Luc) HEK293 Reporter Cell has been created to express the STAT3 signaling response element. Stimulation with human IL-11 protein activates the IL-11/IL-11 R alpha interaction, driving STAT3-mediated luminescence. Inhibition of IL-11 binding to IL-11 R alpha with either anti-IL-11 or anti-IL-11 R alpha antibodies results in a decrease in luminescence.
Application
Screen for anti-human IL-11 or anti-human IL-11 R alpha neutralizing antibody.
Background
IL - 11 R alpha (Interleukin 11 Receptor Alpha) is a cell - surface receptor that binds interleukin - 11 (IL - 11). It plays roles in hematopoiesis, bone metabolism, and tissue repair by mediating the biological effects of IL - 11, such as stimulating cell proliferation and differentiation in various cell types.
Product Information
| Category | Cytokine Receptor Cell Lines |
| Cell Line Name | HEK293-Human IL-11 R alpha (Luc)-Reporter Cell |
| Protein Family | Interleukin receptor family |
| Gene | IL-11 R alpha |
| NCBI Gene ID | IL - 10 R alpha: 3587 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |