HEK293-Human IL-2 R beta/IL-2 R gamma (Luc)-Reporter Cell
| Catalog Number | CBCL-0202 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell has been engineered to express the STAT5 signaling response element, as well as the full-length human IL-2 R beta (Uniprot: P14784) and IL-2 R gamma (Uniprot: P31785-1) receptors. Stimulation with human IL-2 protein activates receptor-mediated signaling, driving STAT5-mediated luminescence.
Application
Bioactivity detection of human IL-2 fusion protein
Background
IL - 2 R beta and IL - 2 R gamma are subunits of the interleukin - 2 receptor. Along with IL - 2 R alpha, they form a high - affinity receptor complex for IL - 2, a cytokine important for T - cell proliferation, differentiation, and immune regulation. The gamma chain is also shared by other cytokine receptors.
Product Information
| Category | Cytokine Receptor Cell Lines |
| Cell Line Name | HEK293-Human IL-2 R beta/IL-2 R gamma (Luc)-Reporter Cell |
| Protein Family | Interleukin receptor family |
| Gene | IL-2 R beta/IL-2 R gamma |
| NCBI Gene ID | IL - 2 R beta: 3560 IL - 2 R gamma: 3561 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.