Catalog Number | CBCL-0202 |
Price | Online Inquiry |
Unit Quantity | 5 x 10^6 cells / 1.0 ml |
The Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell has been engineered to express the STAT5 signaling response element, as well as the full-length human IL-2 R beta (Uniprot: P14784) and IL-2 R gamma (Uniprot: P31785-1) receptors. Stimulation with human IL-2 protein activates receptor-mediated signaling, driving STAT5-mediated luminescence.
Bioactivity detection of human IL-2 fusion protein
IL - 2 R beta and IL - 2 R gamma are subunits of the interleukin - 2 receptor. Along with IL - 2 R alpha, they form a high - affinity receptor complex for IL - 2, a cytokine important for T - cell proliferation, differentiation, and immune regulation. The gamma chain is also shared by other cytokine receptors.
Category | Cytokine Receptor Cell Lines |
Cell Line Name | HEK293-Human IL-2 R beta/IL-2 R gamma (Luc)-Reporter Cell |
Protein Family | Interleukin receptor family |
Gene | IL-2 R beta/IL-2 R gamma |
NCBI Gene ID | IL - 2 R beta: 3560 IL - 2 R gamma: 3561 |
Species | Human |
Host Cell Line | HEK293 |
Cell Type | Human embryonic kidney cells |
Morphology | Epithelial |
Growth Properties | Adherent |
Selection Marker | Puromycin (2 μg/mL) + Zeocin (20 μg/mL) + G418 (200 μg/mL) |
Recommended Medium | DMEM + 10% FBS |
Freeze Medium | Serum-free cell cryopreservation medium |
Storage Method | Frozen in liquid nitrogen. |
Stability | Validated for at least 10 passages |
Mycoplasma | Negative |
Sterility Testing | Negative |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |