HEK293-Human PD-L1, GFP Tag-Stable Cell Line
| Catalog Number | CBCL-0592 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-Human PD-L1, GFP Tag-Stable Cell Line is used for binding assays by FACS and cell-based ELISA.
Application
Human PD-L1, GFP Tag-HEK293 cells stably expressing exogenous human PD-L1 (Programmed cell death 1 ligand 1, CD274, B7-H1, PDCD1L1, PDCD1LG1, AA sequence : Leu 19 - Leu 238, Protein Acc.# : Q9NZQ7-1). At the same time, GFP protein as a marker was expressed in HEK239/hPD-L1 cells for screening positive cells by FACS.
Background
PD-L1 (Programmed Death-Ligand 1, CD274) is an immune checkpoint molecule expressed on tumor cells, macrophages, and dendritic cells. It binds to PD-1 on T cells, delivering inhibitory signals that suppress T cell activation and promote immune evasion. PD-L1 overexpression correlates with poor cancer prognosis and resistance to immunotherapy.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | HEK293-Human PD-L1, GFP Tag-Stable Cell Line |
| Protein Family | Programmed cell death ligand 1 family |
| Gene | PD-L1 |
| NCBI Gene ID | 29126 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |