HEK293-Human SIRP alpha-Stable Cell Line
| Catalog Number |
CBCL-0597 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
The HEK293-Human SIRP alpha-Stable Cell Line is a stable cell line expressing human SIRP alpha.
Application
Drug screening and biological assays
Background
SIRPα (Signal Regulatory Protein Alpha) is an inhibitory receptor expressed on macrophages and dendritic cells. It binds to CD47 on normal cells and tumor cells, delivering inhibitory signals that suppress phagocytosis. Tumor cells overexpress CD47 to evade SIRPα-mediated clearance, making SIRPα-CD47 axis a target for cancer immunotherapy.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
HEK293-Human SIRP alpha-Stable Cell Line |
| Protein Family |
Signal regulatory protein family |
| Gene |
SIRP alpha |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin (5 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
10% DMSO + 90% FBS |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
