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HEK293-Human TSHR-Stable Cell Line

Catalog Number CBCL-0046
Price Online Inquiry
Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

A stable HEK293 cell line expressing the human thyroid-stimulating hormone receptor (TSHR). This cell line is useful for studying the interactions of TSHR with its ligands and its role in various cellular processes.

Application

Useful for cell-based TSHR binding assay

Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. It is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.

Product Information

Category GPCR Cell Lines
Cell Line Name HEK293-Human TSHR-Stable Cell Line
Protein Family Thyroid-stimulating hormone receptor
Gene TSHR
NCBI Gene ID 7253
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Selection Marker Hygromycin B (20 μg/mL)
Recommended Medium DMEM medium + 10% FBS
Freeze Medium Serum-free cell cryopreservation medium
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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