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HEK293-Human TSHR-Stable Cell Line

Catalog Number CBCL-0046
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Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

A stable HEK293 cell line expressing the human thyroid-stimulating hormone receptor (TSHR). This cell line is useful for studying the interactions of TSHR with its ligands and its role in various cellular processes.

Application

Useful for cell-based TSHR binding assay

Background

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. It is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.

Product Information

Category GPCR Cell Lines
Cell Line Name HEK293-Human TSHR-Stable Cell Line
Protein Family Thyroid-stimulating hormone receptor
Gene TSHR
NCBI Gene ID 7253
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.