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HEK293-IL-31 Responsive Luciferase Reporter-Stable Cell Line

Catalog Number CBCL-0728
Price Online Inquiry
Unit Quantity 2 x 10^6 cells / 1.0 ml

Introduction

The HEK293-IL-31 Responsive Luciferase Reporter-Stable Cell Line expresses the human IL-31 receptor complex and has been generated by lentiviral transduction of STAT3 Luciferase Reporter HEK293 cells. IL-31 activity in this cell line can be monitored by measuring luciferase activity.

Application

Drug screening and biological assays

Background

IL - 31 (Interleukin - 31) is a cytokine that is mainly produced by activated T cells, especially Th2 cells. It acts on its receptor complex composed of IL - 31RA and OSMR, and is involved in the regulation of immune responses, inflammation, and has been implicated in skin diseases such as atopic dermatitis.

Product Information

Category Cell Signaling Cell Lines
Cell Line Name HEK293-IL-31 Responsive Luciferase Reporter-Stable Cell Line
Protein Family Interleukin receptor family
Gene IL-31
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Recommended Medium DMEM medium + 10% FBS
Freeze Medium 90% FBS + 10% DMSO
Storage Method Liquid Nitrogen
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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