HEK293-ISRE (Luc)-Reporter Cell
| Catalog Number | CBCL-0212 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
he ISRE (Luc) HEK293 Reporter Cell was designed to express IFN-stimulated response elements (ISRE) that drive luciferase expression. When stimulated with human Type I interferons (IFNs), receptor-mediated signaling can trigger IFN-stimulated gene factor 3 (ISGF3)-mediated luminescence.
Application
Screen for activators or inhibitors of Type I interferons.
Background
ISRE (Interferon - Stimulated Response Element) is a cis - acting DNA element found in the promoter regions of interferon - stimulated genes. It is recognized and bound by transcription factors activated by interferons, leading to the transcriptional activation of these genes and the induction of an antiviral and immune - regulatory response.
Product Information
| Category | Cytokine Receptor Cell Lines |
| Cell Line Name | HEK293-ISRE (Luc)-Reporter Cell |
| Protein Family | Interferon-stimulated response element family |
| Gene | ISRE |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.