HEK293-MATE2K-Cell line
| Catalog Number | CBCL-0680 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A recombinant HEK293 cell line engineered to express human MATE2K (multidrug and toxin extrusion protein 2K).
Application
Drug screening and biological assays
Background
Multidrug and toxin extrusion protein 2-K (MATE2K), also known as SLC47A2, is another member of the MATE family of transporters. It shares overlapping substrate specificity with MATE1 and is expressed primarily in the kidney, where it mediates the tubular secretion of various organic cations. MATE2K plays a role in renal drug elimination and is subject to regulation by various factors.
Product Information
| Category | SLC Transporter Cell Lines |
| Cell Line Name | HEK293-MATE2K-Cell line |
| Protein Family | Multidrug and toxin extrusion protein family |
| Gene | MATE2K |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | DMEM medium + 10% FBS |
| Freeze Medium | 80% DMEM + 10% FBS + 21% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.