HEK293-NFAT (Luc)-Reporter Cell
| Catalog Number |
CBCL-0252 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
This HEK293-based reporter cell line incorporates the NFAT response element to drive luciferase expression. Receptors that are either endogenously expressed or transfected into these cells can be activated by their respective ligands.
Application
The discovery of activators or inhibitors by the NFAT signaling bioactivity
Background
NFAT (Nuclear Factor of Activated T Cells) is a transcription factor that regulates gene expression in response to calcium signaling in T cells and other immune cells.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
HEK293-NFAT (Luc)-Reporter Cell |
| Protein Family |
Nuclear factor of activated T-cells family |
| Gene |
NFAT |
| NCBI Gene ID |
NFATC1/4772 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (50 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
