HEK293-OAT3-Cell line
| Catalog Number |
CBCL-0674 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
A recombinant HEK293 cell line that expresses human OAT3 (organic anion transporter 3).
Application
Drug screening and biological assays
Background
Organic anion transporter 3 (OAT3), also known as SLC22A8, is another renal organic anion transporter that shares overlapping substrate specificity with OAT1. It mediates the tubular secretion of various organic anions and plays a role in drug disposition and renal clearance. OAT3 is also expressed in other tissues, including the brain and liver, and may play a role in drug distribution and elimination in these organs.
Product Information
| Category |
SLC Transporter Cell Lines |
| Cell Line Name |
HEK293-OAT3-Cell line |
| Protein Family |
Organic anion transporter family |
| Gene |
OAT3 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
80% DMEM + 10% FBS + 15% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
