HEK293-OATP2B1-Cell line
| Catalog Number | CBCL-0671 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A recombinant HEK293 cell line engineered to express human OATP2B1 (organic anion transporting polypeptide 2B1).
Application
Drug screening and biological assays
Background
Organic anion transporting polypeptide 2B1 (OATP2B1), also known as SLCO2B1, is a membrane transporter protein expressed in various tissues, including the liver, intestine, and kidney. It mediates the uptake of a wide range of organic anions, including drugs, hormones, and toxins, into cells. OATP2B1 plays a role in drug absorption, distribution, and elimination and is subject to regulation by various factors, including hormones and drugs.
Product Information
| Category | SLC Transporter Cell Lines |
| Cell Line Name | HEK293-OATP2B1-Cell line |
| Protein Family | Organic anion transporting polypeptide family |
| Gene | OATP2B1 |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | DMEM medium + 10% FBS |
| Freeze Medium | 80% DMEM + 10% FBS + 12% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.