HEK293-PDE1B-Recombinant Cell Line
| Catalog Number |
CBCL-0663 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
A recombinant HEK293 cell line created to express human PDE1B (phosphodiesterase 1B, accession number NM_000924). This cell line includes N-terminal His-tagged human PDE1B, with stable expression confirmed by Western blotting. The functionality of PDE1B was evaluated through a cell-based cGMP assay.
Application
Drug screening and biological assays
Background
PDE1B (Phosphodiesterase 1B) is a dual - substrate phosphodiesterase that can hydrolyze both cAMP and cGMP. It is expressed in various tissues including the brain and plays a role in neuronal signaling and other cellular functions.
Product Information
| Category |
Phosphodiesterases Cell Lines |
| Cell Line Name |
HEK293-PDE1B-Recombinant Cell Line |
| Protein Family |
Phosphodiesterase family |
| Gene |
PDE1B |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
