HEK293-PDE1B-Recombinant Cell Line
| Catalog Number | CBCL-0663 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A recombinant HEK293 cell line created to express human PDE1B (phosphodiesterase 1B, accession number NM_000924). This cell line includes N-terminal His-tagged human PDE1B, with stable expression confirmed by Western blotting. The functionality of PDE1B was evaluated through a cell-based cGMP assay.
Application
Drug screening and biological assays
Background
PDE1B (Phosphodiesterase 1B) is a dual - substrate phosphodiesterase that can hydrolyze both cAMP and cGMP. It is expressed in various tissues including the brain and plays a role in neuronal signaling and other cellular functions.
Product Information
| Category | Phosphodiesterases Cell Lines |
| Cell Line Name | HEK293-PDE1B-Recombinant Cell Line |
| Protein Family | Phosphodiesterase family |
| Gene | PDE1B |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.