HEK293-SLC5A5-Recombinant Cell Line
| Catalog Number |
CBCL-0666 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
A stable recombinant HEK293 cell line expressing human SLC5A5 (UniProt # Q92911) with a C-terminal FLAG-tag. SLC5A5 is a sodium-dependent iodide transporter and a member of the sodium glucose co-transporter family. Expression of SLC5A5 has been confirmed by Western blotting. This cell line can be utilized to evaluate agents that may impact iodide transport.
Application
Drug screening and biological assays
Background
SLC5A5 (Solute Carrier Family 5 Member 5) is a sodium - iodide symporter. It is mainly expressed in the thyroid gland and is responsible for the active uptake of iodide into thyroid follicular cells, which is essential for thyroid hormone synthesis.
Product Information
| Category |
Ion Channel Cell Lines |
| Cell Line Name |
HEK293-SLC5A5-Recombinant Cell Line |
| Protein Family |
Solute carrier family |
| Gene |
SLC5A5 |
| NCBI Gene ID |
6571 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
