HEK293-STAT3 (Luc)-Reporter Cell
| Catalog Number |
CBCL-0260 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
This HEK293 reporter cell line incorporates the STAT3 response element to drive luciferase expression. Receptors that are either endogenously expressed or transfected into these cells can be activated by their respective ligands. This activation leads to intracellular signaling, culminating in STAT3-RE mediated luminescence.
Application
The discovery of activators or inhibitors by the STAT3 signaling bioactivity.
Background
STAT3 is a transcription factor that regulates gene expression in response to cytokines and growth factors. It plays a role in cell growth, proliferation, survival, and immune responses.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
HEK293-STAT3 (Luc)-Reporter Cell |
| Protein Family |
Signal transducer and activator of transcription family |
| Gene |
STAT3 |
| NCBI Gene ID |
6774 |
| Species |
Human |
| Host Cell Line |
HEK293 |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (40 μg/mL) |
| Recommended Medium |
DMEM medium + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
