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HEK293T-AR-L702H-HiBiT-Stable Cell Line

Catalog Number CBCL-0375
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

This stable HEK293T cell line expresses exogenous AR with an L702H mutation and a HiBiT tag, facilitating studies of AR signaling and activity.

Application

Drug screening and biological assays

Background

AR L702H is a point mutation in the androgen receptor (AR) gene, potentially altering AR function and associated with prostate cancer progression and resistance to therapy.

Product Information

Category Fluorescence Labeled Cell Lines
Cell Line Name HEK293T-AR-L702H-HiBiT-Stable Cell Line
Protein Family Androgen receptor family
Gene AR L702H
Species Human
Host Cell Line 293T
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin
Recommended Medium DMEM+10%FBS+1μg/mL puromycin
Freeze Medium 70% DMEM+20% FBS+10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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