HEK293T-CRE-Luc2-GLP1R-T2A-GIPR-Stable Cell Line
| Catalog Number |
CBCL-0309 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This stable HEK293T cell line expresses exogenous luciferase under the control of the cAMP response element (CRE) and also expresses GLP1R and GIPR, enabling studies of CRE-dependent gene expression and signaling events.
Application
Drug screening and biological assays
Background
GLP1R and GIPR are G protein-coupled receptors for glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), respectively. They play key roles in regulating glucose homeostasis and insulin secretion.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
HEK293T-CRE-Luc2-GLP1R-T2A-GIPR-Stable Cell Line |
| Protein Family |
Glucagon-like peptide-1 receptor family; G protein-coupled receptor family |
| Gene |
GLP1R; GIPR |
| NCBI Gene ID |
GLP1R：2740；GIPR：2696 |
| Species |
Human |
| Host Cell Line |
293T |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin |
| Recommended Medium |
DMEM+10%FBS+1µg/ml Puromycin+150µg/ml Hygromycin B |
| Freeze Medium |
70% DMEM+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
