HEK293T-IL2RG-low expression-Stable Cell Line

Catalog Number	CBCL-0430
Price	Online Inquiry
Unit Quantity	1 x 10^6 cells / 1.0 ml

Introduction

The HEK293T-IL2RG-low expression-Stable Cell Line is a stable clone of the HEK293T cell line that expresses the exogenous IL2RG gene at a low level.

Application

Drug screening and biological assays

Background

IL2RG encodes the common gamma chain, a component of multiple cytokine receptors (e.g., IL-2, IL-4, IL-7, IL-9, IL-15, IL-21 receptors), crucial for lymphocyte development and function. Mutations cause X-linked severe combined immunodeficiency (X-SCID).

Product Information

Category	Immune Molecules Cell Lines
Cell Line Name	HEK293T-IL2RG-low expression-Stable Cell Line
Protein Family	Interleukin receptor family
Gene	IL2RG
NCBI Gene ID	3561
Species	Human
Host Cell Line	293T
Cell Type	Human embryonic kidney cells
Morphology	Epithelial
Growth Properties	Adherent
Selection Marker	Puromycin
Recommended Medium	DMEM+10%FBS+10µg/ml Puromycin
Freeze Medium	70% DMEM+20% FBS+10% DMSO
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.