HEK293T-ISRE-Luc2-ADAR1-P150-Reporter Cell Line
| Catalog Number |
CBCL-0271 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This HEK293T cell line has been engineered to express the ISRE (interferon-stimulated response element) driving luciferase 2 (Luc2) expression, and also expresses the ADAR1 P150 protein. This setup allows for the study of interferon signaling and ADAR1 P150 activity through bioluminescence assays.
Application
Drug screening and biological assays
Background
ADAR1-P150 is an isoform of the ADAR1 enzyme, which edits RNA by converting adenosine to inosine. It plays a role in regulating gene expression and immune responses.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
HEK293T-ISRE-Luc2-ADAR1-P150-Reporter Cell Line |
| Protein Family |
Adenosine deaminases acting on RNA family |
| Gene |
ADAR1-P150 |
| NCBI Gene ID |
105 |
| Species |
Human |
| Host Cell Line |
293T |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B |
| Recommended Medium |
DMEM+10%FBS+140µg/mL Hygromycin B |
| Freeze Medium |
70% DMEM+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
