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HER2 Stable T47D Cell Line

Catalog Number CBCL-432
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable T47D cell clone expressing exogenous HER2 gene.

Application

Drug screening and biological assays

Background

HER2, also named ERBB2, is a cell-surface receptor tyrosine kinase, ERBB2 overexpression or overactivity have associated with a number of cancers, especially the breast cancer. The identification of ERBB2 as a driver gene has led to the development of anticancer therapeutics agents.

Product Information

Species Human
Host Cell Line T47D cell line
Cell Type Mammary gland epithelial cells
Stability Stable in culture over 10 passages
Growth Properties Adherent
Pharmaceutical Target Immune Molecules
Recommended Medium RPMI 1640 + 10% FBS + 500 μg/ml G418
Selection Marker Neomycin
Morphology Epithelial
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time Approximately 30 hours
QC WB
Biosafety Level BSL-1
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.
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