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Human ARv7 Stable HEK293 Cell Line

Catalog Number CBCL-382
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable HEK293 cell line expressing exogenous human ARv7 gene

Application

Drug screening and biological assays

Background

ARv7, also known as AR3. As the most common AR-V, the androgen receptor splice variant 7 (AR-V7), a splice variant of the androgen receptor mRNA resulting in the truncation of the ligand-binding domain, is a promising predictive tumor marker and a relevant selection marker for the treatment of advanced prostate cancer.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Human ARv7 Stable HEK293 Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Monolayer
Growth Properties Adherent
Selection Marker Puromycin and hygromycin B
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 30 hours
Recommended Medium DMEM + 10% FBS + 1 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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