| Catalog Number | CBCL-382 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Stable HEK293 cell line expressing exogenous human ARv7 gene
Drug screening and biological assays
ARv7, also known as AR3. As the most common AR-V, the androgen receptor splice variant 7 (AR-V7), a splice variant of the androgen receptor mRNA resulting in the truncation of the ligand-binding domain, is a promising predictive tumor marker and a relevant selection marker for the treatment of advanced prostate cancer.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human ARv7 Stable HEK293 Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin and hygromycin B |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:5. |
| Doubling Time | Approximately 30 hours |
| Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |